AVALIAÇÃO DA FUNÇÃO RENAL EM CÃES NÃO AZOTÊMICOS IDOSOS

Abstract

Renal health is fundamental to animal welfare, but can be harmed by conditions such as acute kidney injury and chronic kidney disease, which makes biomarkers evaluation important in order to increase longevity and quality. of life of the geriatric patients. The objective of this study was to evaluate the kidney health of non-azothemical elderly dogs through routine biomarkers such as UPC (protein/creatinine relationship), urinesis, fractional chloride excretion (FECl), urinary gamma-gammiltransferase (uGGT) and phosphate Urinary Alkaline (uALP) in the early identification of renal injury and compare with structural changes through renal ultrasound. In a total of 106 dogs evaluated, 74 animals were selected for the elderly group aged 7 to 17 years and 12 dogs of the young group aged 1 to 4 years. Animal animals with serum creatinine (sCr)> 1.4 mg/dL, or pre-existing diseases were excluded from the study. Performed the exams of blood count, serum biochemicals: sCr, urea, alkaline phosphatase, alanine aminotransferase, sodium and potassium, and urinary: UPC, uGGT, uALP and FECl, as well as urinalysis. In a portion of dogs that had a change in the UPC exam, ultrasound exam was performed. Statistical differences were found in UPC exams and uGGT/uCr ratio (p <0.05). UPC and uGGT exams were effective in detecting renal injury when compared to other tests such as serum creatinine and urea, and FECl. These tests, together with ultrasound evaluation, assist the clinician in the best management of the elderly patient.